
痛くない乳がん検診:MRI DWIBS法 Painless Breast Cancer Screening: DWIBS MRI | 高原 太郎 Taro Takahara | TEDxTeikyoU
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The speaker, specializing in diagnostic imaging, discusses the evolution of medical practices, particularly regarding pain management and diagnostic accuracy, drawing parallels to historical medical advancements. Over 200 years ago, Hanaoka Seishun pioneered general anesthesia, known as "Total," enabling patients to undergo surgery, such as eye surgery, while asleep. This marked a shift in medicine towards compassion, moving away from the excruciating pain previously associated with surgery.
The speaker highlights that even today, medical procedures can be painful. Mammography, a primary method for breast cancer screening, involves firmly compressing the breast, which can be very painful. A systematic review in the UK indicated that women who experienced pain during a previous mammogram were 1.34 times more likely to experience pain in subsequent examinations. The speaker then introduces the idea of a painless and invisible breast cancer detection method that offers clearer visualization, which they achieved with MRI.
A new MRI diagnostic method uses an expander. Initially, without medication to enhance cancerous content, the cancer is not visible. However, with increased medication, the cancer becomes clearly visible, due to the presence of numerous blood vessels that the cancer induces to grow larger by scattering vascular genes. This allows for clear visualization and transfer of the cancer.
The speaker then introduces a treatment plan that does not involve medication to increase dosage. While the main points are visible, surrounding blood vessels are not. The explanation for this lies in the diffusion rate of water in tissues. In normal tissue, water moves freely due to space around cells, resulting in a high diffusion rate. In cancerous tissue, which tends to grow densely, water movement is restricted, leading to a low diffusion rate.
A diffusion-weighted image displays tissue with low diffusion as white, suppressing signals from normal tissue to create contrast. This imaging technique was initially used for diagnosing cerebral infarction but was adapted to identify cancer throughout the body six years later in 2004, exactly 200 years after Seishun Hanaoka developed liquid medicine. The speaker named this the "Doibs method."
Despite its positive reception at academic conferences, the speaker initially refrained from using the Doibs method for personal spiritual work, believing that insured medical care for patients was the essence of medicine, and that devotion to work should be for healthy individuals, not for commercial gain.
However, eight years later, a personal tragedy changed the speaker's perspective. After his mother's funeral, his father revealed he had lost his appetite and weight. The following day, the speaker performed the Dowibs procedure on his father at the university hospital, discovering a large, 10 cm colon cancer with extensive metastases to the liver and lymph nodes, classifying it as Stage 4.
The Doibs procedure proved exceptionally effective for monitoring treatment. The speaker observed a decrease in the occupancy signal in just one week and a reduction in occupancy in one month, bringing hope to his father. Later, these black and white images could be converted to color, with pre-treatment conditions displayed in red and post-treatment, when cell numbers decreased and water mobility increased, displayed in yellow or green.
Despite initial improvements, the persistence of red areas in the images indicated that some "cow-like qualities" of the cancer remained, suggesting it was still active. Subsequent experience showed that if red color remained, the disease often worsened again. The speaker's father, despite his artistic pursuits, lost energy after about six months of treatment and passed away within a year of symptom onset.
The speaker expressed profound regret and self-blame, feeling that he had failed to save his father due to not fully utilizing his knowledge and the Doibs method earlier. This painful experience led him to dedicate himself to making the Doibs method widely available.
Collaborating with a teacher, a full-body heart scan was performed, and a new, painless MRI method without an amplifying agent was developed. A key innovation was the ability to film while patients were clothed, resulting in the world's first painless, invisible breast donation screening in Japan. The Doibs method effectively reduces fat, allowing for clear visualization inside the mammary glands, even identifying tiny 6mm papillae.
This advancement enables potential non-surgical healing for tumors up to 15mm using cryotherapy, a one-hour outpatient procedure where a rod is inserted to cool and kill tissue. For larger tumors requiring surgery, the 3D visualization offered by the Doibs method is highly beneficial for pinpointing locations.
The Doibs method also incorporates "fusion," where another image is overlaid to concretely display information, allowing for precise identification of the main focus within a target area. This is particularly useful for needle biopsies, enabling immediate diagnosis.
Currently, this screening program is available at approximately 100 hospitals, with 60,000 people having received it. A survey indicates that about one-third of respondents choose this as their first prenatal checkup, meaning 20,000 people in Japan have experienced breast cancer screening without pain. The speaker believes that eliminating pain is not a sign of weakness but an advancement in medicine, and he intends to continue working towards a society where "nursing and devotion" are not associated with pain. He encourages everyone to get their minds checked.